Updates from the SCRC


For People with Lived Experience of Cancer

New Research Study: Help Us Understand Fatigue After Breast Cancer Treatment

We are excited to announce that recruitment has opened for a new research study funded by the Sussex Cancer Fund and sponsored by the University of Brighton. The study will explore why some women feel more fatigued, sometimes months after their breast cancer treatment is finished.

Who can take part? We are looking for women aged 18–60 who are experiencing fatigue and are in remission from breast cancer (with treatment completed within the last 24 months). We are also looking for women who are aged 18–60, healthy, and are not experiencing fatigue for a comparison group.

What is the study about? Fatigue is one of the most common and distressing symptoms reported by people living with and beyond cancer. Despite how widespread it is, we still don’t fully understand what causes it or how to treat it effectively. In this study, we will explore the hypothesis that cancer and its treatments could change how the brain interprets signals from the body – such as heartbeat, temperature, and muscle exertion – potentially making everyday activities feel more tiring than they should. By understanding this brain–body connection, researchers hope to reveal why fatigue affects some women more severely than others – and why some may feel particularly fatigued during exercise. This insight is especially valuable because regular exercise is actually recommended to help manage cancer-related fatigue. Ultimately, the study hopes to make recovery smoother and more effective.

What does taking part involve? The team will first provide you with information about the study and give you time to consider what is involved and ask any questions. If you decide to take part, you will be invited to attend a visit lasting approximately 3 hours, at the University of Brighton’s Falmer campus. On the day of your visit, you will be met by one member of the research team who will remind you of what is involved, answer your questions and provide you with a consent form to sign. We will ask for your permission to collect some information from your medical records. Then you will be asked to complete some questionnaires, have a go at some non-invasive physical tasks, including a hand grip exercise and three tests that explore your ability to recognise different sensations. Lastly you will be asked to provide a small saliva sample. During the visit you will be welcome to take breaks or choose to stop completely if you wish to do so.

Please note: The aim of this research study is to collect data that will help us generate new scientific knowledge. The team is not testing a treatment, and there is no expected direct benefit to participants. However, it is anticipated that your involvement will contribute to a better understanding of cancer-related fatigue and you may help improve care for others in the future. Thank you for reading this information. If you are interested in finding out more, please get in touch with Rowan via CRFStudy@brighton.ac.uk or 01273 6413731.

Sussex Cancer Research Centre

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